Reversing Antidepressant Weight Gain
Reversing Antidepressant Weight Gain By Judith J. Wurtman, PhD, Co-author of The Serotonin Power Diet: Eat Carbs -- Nature's Own Appetite Suppressant -- to Stop Emotional Overeating and Halt Antidepressant-Associated Weight Gain Antidepressants have been associated with weight gain since they were first used about 50 years ago. Tricyclic antidepressants (TCA) relieved depression but left patients considerably heavier as a consequence of treatment. One in particular, amitryptyline, was associated with uncontrollable sugar cravings. When Selective Serotonin Re-uptake Blockers (SSRIs) were introduced as the new generation of antidepressants, it was hoped that weight gain would not be a problem. Unfortunately this expectation has not been realized. Clinician were optimistic about Prozac, the first of the SSRIs, as patients lost weight during the early months of treatment. Prozac was viewed not only as an effective mood regulator but a potential weight-loss drug as well. It was tested i...